Endocrine Abstracts

Background: Bardet-Biedl syndrome (BBS) is a rare melanocortin-4 receptor (MC4R) pathway disease characterized by early-onset, severe obesity and hyperphagia associated with primary cilia dysfunction. Patients with rare MC4R pathway diseases of obesity and hyperphagia, including BBS, experience high disease burden, but the relationship between hyperphagia and body weight in patients with BBS is not fully understood. We assessed the correlation between hyperphagia score and obe...